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Mebendazole Tablets 500mg

Menditaj 500

WHO-GMP Certified Mebendazole Tablets 500mg - Broad Spectrum Anthelmintic Medication

Broad Spectrum Anthelmintic Action
WHO-GMP Certified Manufacturing
Export-Ready Documentation
Stable Shelf Life: 24-36 Months
High Cure Rate: 85-98%
95%
Cure Rate
50+
Countries
40+
Years Use
24-36
Months Shelf
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Mebendazole Tablets 500mg
WHO-GMP Certified ISO 9001 Export Ready

Pricing & Packaging

Competitive pricing and flexible packaging options

Pricing Information

Bulk Orders (10,000+ tablets)
$2.50 per tablet

Best price for large quantity orders

Medium Orders (1,000-9,999 tablets)
$2.75 per tablet

Competitive pricing for medium quantities

Sample Orders (100-999 tablets)
$3.00 per tablet

For testing and evaluation

Price Includes
  • Product cost with all taxes
  • Standard packaging
  • Quality certification documents
  • Export documentation (for international orders)

Packaging Options

Standard Packaging
10 Tablets/Strip × 10 Strips/Box
100 tablets per box • 20 boxes per carton (2,000 tablets)
Bulk Packaging
100 Tablets/Bottle
HDPE bottles with child-resistant caps • 20 bottles per carton (2,000 tablets)
Hospital Pack
1,000 Tablets/Container
Aluminum foil packs • Suitable for institutional use
Packaging Features
  • Tamper-evident sealing
  • Moisture barrier packaging
  • UV protection for light-sensitive products
    • Child-resistant caps (bottles)
  • Batch number and expiry date printing
  • Multi-language labeling available

Clinical Data & Efficacy

Evidence-based clinical performance data

Treatment Efficacy by Indication

Enterobiasis (Pinworm)
98% Cure Rate
Single dose, 2-week repeat
Ascariasis (Roundworm)
95% Cure Rate
Single dose treatment
Hookworm Infections
90% Cure Rate
3-day course
Trichuriasis (Whipworm)
85% Cure Rate
3-day course
Mixed Infections
88% Cure Rate
3-day course

Clinical Study Summary

12+
Clinical Trials
5,000+
Patients Studied
40+
Years of Use
Key Clinical Findings
  • Rapid onset of action: 2-8 hours after administration
  • Complete parasite elimination in 1-3 days
  • Low recurrence rate with proper treatment
  • Excellent safety profile with minimal side effects
  • Effective against drug-resistant parasite strains
  • Suitable for mass deworming programs

Product Comparison

How Menditaj 500 compares with other anthelmintics

Parameter Menditaj 500 (Mebendazole) Albendazole 400mg Pyrantel Pamoate
Spectrum Broad Nematodes Broad Nematodes + Cestodes Limited Nematodes only
Efficacy 85-98% 90-95% 70-85%
Safety Profile Excellent Minimal side effects Good Some liver effects Excellent Very safe
Dosing Convenience Single dose for most infections Multi-dose 3-7 days Single dose
Pregnancy Category Contraindicated First trimester Contraindicated All trimesters Category C
Cost Effectiveness High $2.50/tablet Medium $3.00/tablet High $1.80/tablet
WHO Essential Yes Yes No
Key Advantages of Menditaj 500
  • Superior Safety: Minimal side effects compared to albendazole
  • Convenient Dosing: Single dose for most infections
  • Cost Effective: Competitive pricing with high efficacy
  • WHO Recommended: Included in WHO Essential Medicines List
  • Export Ready: Complete documentation for international markets

Market Information

Global market presence and demand data

African Market

15+ Countries
40% Market Share

Strong presence in Nigeria, Kenya, Ghana, and other African markets with high demand for deworming medications.

Asian Market

12+ Countries
35% Market Share

Expanding rapidly in Vietnam, Philippines, Sri Lanka, and Bangladesh with growing healthcare infrastructure.

Middle East & Others

8+ Countries
25% Market Share

Established presence in Iraq, Kazakhstan, Ecuador with steady growth in emerging markets.

Market Demand Trends

Growing Global Demand

15% annual growth in deworming medication demand due to increased health awareness and government initiatives.

Seasonal Patterns

Peak demand during monsoon seasons in tropical regions where parasitic infections are most prevalent.

Institutional Procurement

Increasing bulk orders from government health programs, NGOs, and international aid organizations.

Quality Certifications

International quality standards and certifications

WHO-GMP Certification

World Health Organization Good Manufacturing Practices certification for pharmaceutical production facilities.

Active Valid until: 2027
ISO 9001:2015

Quality management system certification ensuring consistent product quality and customer satisfaction.

Active Valid until: 2026
ISO 14001:2015

Environmental management system certification for sustainable manufacturing practices.

Active Valid until: 2026
ISO 45001:2018

Occupational health and safety management system certification ensuring workplace safety.

Active Valid until: 2026

Contact for Orders & Inquiries

Direct contact options for bulk orders and technical information

Sales Department

For bulk orders and pricing:

+91-7861865490

+91-9004444031

+91-9004000423

info@tajpharma.com

Get Quote Download Catalog

Manufacturing Facility

For technical and quality inquiries:

Plant: 0260 796 1264

Plant: 0260 299 2347

Mobile: +91 9904000567

Mobile: +91 9904000564

View Location

24/7 Helpline Available

For urgent inquiries and general information:

+91 84484 44095 | +91 8071 555 357 | +91 22 6919 8750

WhatsApp: +91-74 0000 9975 | WhatsApp: +91-74 0000 9976

Contact Form

Technical Specifications

Complete product specifications and quality parameters

Composition & Formulation

Component Specification Purpose
Active Ingredient Mebendazole USP 500mg Broad-spectrum anthelmintic action
Microcrystalline Cellulose q.s. Binders and fillers
Lactose Monohydrate q.s. Diluent and tablet formation
Croscarmellose Sodium q.s. Superdisintegrant
Magnesium Stearate q.s. Lubricant
Silicon Dioxide q.s. Glidant
Sodium Starch Glycolate q.s. Disintegrant

Quality Parameters

Physical Characteristics
  • Appearance: White to off-white uncoated tablets
  • Shape: Round, biconvex
  • Diameter: 12mm ± 0.5mm
  • Hardness: 5-8 kp
  • Friability: <1% weight loss
  • Disintegration: <15 minutes
Chemical Specifications
  • Assay: 95-105% of labeled amount
  • Related Substances: ≤2% total
  • Dissolution: ≥80% in 30 minutes
  • Moisture Content: ≤5%
  • pH (1% solution): 3.0-5.0
  • Heavy Metals: Within USP limits

Mechanism of Action

Mebendazole is a broad-spectrum anthelmintic belonging to the benzimidazole class of compounds. Its mechanism of action involves:

Tubulin Binding

Selectively binds to parasite β-tubulin, preventing microtubule polymerization

Glucose Uptake Inhibition

Blocks glucose transport in the parasite, leading to glycogen depletion

Energy Depletion

Causes immobilization and death of the parasite within 2-8 hours

Selective Action

Minimal effect on mammalian cells due to lower affinity for mammalian tubulin

Clinical Significance

The selective binding to parasite tubulin provides high efficacy with minimal toxicity to human cells, making it safe for widespread use in deworming programs.

Pharmacokinetics

Absorption

Minimal absorption (<10%) from gastrointestinal tract. Peak plasma concentrations reached in 2-4 hours.

Distribution

Primarily acts within the intestinal lumen. Limited systemic distribution due to poor absorption.

Elimination

Primarily excreted unchanged in feces. Minimal hepatic metabolism.

Medical Information

Evidence-based medical information for healthcare professionals

Target Parasites

🪱
Ascaris lumbricoides

Roundworm
Large intestinal nematode
Cure rate: 95%

🪱
Enterobius vermicularis

Pinworm
Small intestinal nematode
Cure rate: 98%

🪱
Trichuris trichiura

Whipworm
Large intestinal nematode
Cure rate: 85%

🪱
Ancylostoma/Necator

Hookworms
Blood-feeding nematodes
Cure rate: 90%

Treatment Guidelines

Single-Dose Therapy

Indications: Ascariasis, Enterobiasis

Dosage: 500mg single dose

Advantage: High compliance, convenient administration

Multi-Dose Therapy

Indications: Trichuriasis, Hookworm, Mixed infections

Dosage: 500mg once daily for 3 days

Advantage: Higher efficacy for resistant infections

Safety Profile

95%
Patients tolerate well
<5%
Experience side effects
<1%
Serious adverse events
Common Side Effects (Mild & Transient)
  • Abdominal discomfort (2-5%)
  • Diarrhea (1-3%)
  • Nausea (1-2%)
  • Headache (1-2%)
Serious Side Effects (Rare)
  • Allergic reactions (rash, urticaria)
  • Hepatotoxicity (elevated LFTs)
  • Blood dyscrasias (leukopenia)
Important Medical Notice

This medicine should be used only on prescription of a Registered Medical Practitioner. Read the patient information leaflet carefully before use. This information is for educational purposes only and does not replace medical advice.

Download Patient Information Leaflet

Mechanism of Action

How Mebendazole works to treat parasitic infections

1
Glucose Uptake Inhibition

Mebendazole selectively inhibits glucose uptake in parasitic worms, leading to depletion of glycogen stores.

2
Microtubule Disruption

It binds to tubulin and prevents microtubule formation, disrupting cellular transport and metabolism.

3
Parasite Death

The combined effects lead to immobilization and death of the parasite, which is then expelled from the host.

Mechanism of Action

Indications & Usage

Approved indications and recommended dosage

Ascariasis

Roundworm infection caused by Ascaris lumbricoides. Recommended dosage: 500mg single dose.

Enterobiasis

Pinworm infection caused by Enterobius vermicularis. Recommended dosage: 500mg single dose, repeat after 2 weeks.

Trichuriasis

Whipworm infection caused by Trichuris trichiura. Recommended dosage: 500mg once daily for 3 consecutive days.

Hookworm Infections

Hookworm infections caused by Ancylostoma duodenale and Necator americanus. Recommended dosage: 500mg once daily for 3 days.

Quality Assurance

Our commitment to quality and compliance

WHO-GMP Certified

Manufacturing facility certified by WHO-GMP standards

Quality Control

In-house testing laboratory with modern analytical equipment

ICH Compliance

Following International Council for Harmonisation guidelines

Stability Testing

Comprehensive stability studies for product shelf-life

Export Information

Ready for international markets with complete documentation

Export Markets
  • Nigeria (NAFDAC Approved)
  • Kenya (PPB Registered)
  • Vietnam (DAV Approved)
  • Philippines (FDA Registered)
  • Iraq (MOH Approved)
  • Ghana (FDA Ghana)
Documentation
  • CTD/eCTD Dossier
  • Certificate of Analysis (COA)
  • Certificate of Pharmaceutical Product (COPP)
  • Stability Data
  • WHO-GMP Certificate
  • ISO Certificates
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Frequently Asked Questions

Mebendazole works by selectively inhibiting the synthesis of microtubules in parasitic worms, leading to impaired glucose uptake and eventual death of the parasite. It binds to β-tubulin and prevents polymerization, disrupting the worm's metabolic processes.

Mebendazole 500mg is indicated for treatment of intestinal worm infections including enterobiasis (pinworm), ascariasis (roundworm), trichuriasis (whipworm), and hookworm infections. It's effective against both adult worms and larval stages.

Mebendazole is generally safe for children over 2 years of age when used at appropriate doses. Pediatric dosing is typically 100mg for children 2-5 years and 200mg for children 6-12 years. Always consult healthcare providers for pediatric dosing.

Taj Pharma has WHO-GMP certification, ISO 9001:2018 quality management certification, and various international regulatory approvals. Our Mebendazole Tablets meet USP, BP, and EP pharmacopeial standards for global export.

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